We have had enquiries whether beacons can be used on aircraft. While there’s no specific guidance on beacons from aviation authorities, beacons transmit the same radio signals to other Bluetooth devices such as the FitBit, Android Wear, Apple Watch and Bluetooth headphones. These devices are classed as Personal Electronic Devices (PED).
The use of PEDs depends on the airline. Both the FAA and EASA have guidelines for the use of PEDs.
Also, Samsonite sell suitcases (PDF) that include tracker beacons which infers beacons are safe for use when flying. Update: Smart Luggage is No Longer Allowed.